Dr. Mark D. Murphey has been an academic radiologist over 20 years and has directed all of his scholarly activities to his subspecialty of musculoskeletal imaging. In his early years at the University of Kansas, he published the first article on MRI of the sacroiliac joint. In 1993, Dr. Murphey moved to the Armed Forces Institute of Pathology (AFIP), which provided a unique opportunity to understand the pathologic basis of a disease’s radiologic appearance. In 2010-2011, Dr. Murphey was instrumental in the transition from the AFIP to American Institute for Radiologic Pathology (AIRP) as a program of the American College of Radiology (ACR). Dr. Murphey is currently the Physician-in-Chief at the AIRP. In his tenure at the AFIP and the AIRP he has particularly emphasized research on the imaging appearance of musculoskeletal tumors. Dr. Murphey’s academic career has been extraordinarily fulfilling, and he hopes that his efforts have broadened our knowledge and understanding of the imaging of musculoskeletal disease.